Why do my Feet Hurt - The Connection between Neuropathy
and Free Radicals
A recent TIME Magazine cover story, The Secret Killer, (Feb 2004)
elaborated on the extensive amount of research which has now identified
"inflammation" as the underlying cause of most diseases
and chronic conditions, including diabetes, heart disease, arthritis
and many others - not the least of which is neuropathy. And what
lies behind pain and inflammation? Free radical damage!
Most of us have heard the term, "free radicals," - enough
to know that they are undesirable and that they can be counteracted
with antioxidants. However, few individuals understand their true
nature or the significance of the damage they can cause. Free radicals
are the underlying cause of pain and inflammation and they are a
The term free radical refers to a molecule with an unpaired electron.
At the molecular level, electrons are most stable when they are
paired - as in a happy marriage. When they lose their "mate,"
they become extremely volatile until they find a new partner. The
attraction to "pair up" is so strong that it is used by
the body during the immune response to rob electrons from the membranes
of invading organisms. For single-celled bacteria, this means certain
death. Free radicals are also used by the body to initiate the healing
response. So, in some ways free radicals are very important. However,
when the body mobilizes large numbers of free radicals to challenge
an infection or heal an injury, we are often left with an overabundance
of free radicals to deal with.
Free radicals can also be excessively generated as a result of
poor food choices, medicines, air and water pollution and even the
amount of stress we experience. They are the by-products of metabolic
reactions. In a healthy individual, free radicals are kept in check
by antioxidants which are also naturally produced in the body and
provided from healthy foods. However, when poor diet, environmental
pollution, stress, illness or injury cause a disturbance in the
balance between free radicals and antioxidants, serious consequences
Neuropathy results from free radical damage
Free radicals that are left unchecked, steal electrons from healthy
tissues and cellular components, causing a variety of consequences
known as oxidative stress. A chain reaction is set in motion, where
each molecule is transformed into an electron-hungry radical itself.
This "free radical tag" continues non-stop, thousands
of times a second, leaving behind, a wake of damaged tissues. Free
radicals literally unzip the molecular bonds within the tissues
and cellular components of our bodies. They destroy cell membranes,
cellular components and nerve tissue. For those with neuropathy,
the nerve damage results in pain, tingling, numbness and other symptoms.
And that's why your feet hurt!
Free radicals ? Inflammation ? Nerve damage and Tissue death ?
An interesting fact about nerve cells is that they do not divide
or replicate like most other types of cells. When free radicals
cause irreparable damage to nerve cells, they are gone and for the
most part, they cannot be replaced. Pain, numbness and other symptoms
are usually the first indicators of damage that has been going on
a long time - and it means that there is no more time to waste!
The nerve damage and lack of circulation in the feet (also due to
free radical damage) leads to tissue death and to sores that won't
heal. It can often result in amputation.
Alpha Lipoic Acid - the best tool against free radical damage!
Alpha Lipoic acid (ALA) - the active ingredient in Neurelief Foot
Creme, is one of the most powerful antioxidants known. It has been
heavily researched in the area of diabetes and neuropathy and the
latest clinical trials show that it significantly reduces the symptoms
There are several reasons why ALA produces such profound results.
ALA has the ability to regenerate other antioxidants, allowing them
to be reused over and over again in the battle against free radicals.
ALA is also both water and lipid (fat) soluble, which means that
it is effective, both inside and outside the cells of the body.
But perhaps most importantly is the fact that ALA easily penetrates
the tissues of the skin, instantly taking its free radical-balancing
power to the over 1300 nerve endings in each square inch of the
bottom of your feet. Many notice relief in minutes!
If you have neuropathy or any kind of foot pain - you can be sure
free radicals are on the rampage! Now there is something you can
do about it!
Neurelief Foot Creme.
*Be sure to read the next Neurelief Newsletter for the latest research
on Alpha lipoic acid.